Pharmacognostic Study of Ehretia acuminata R.Br.

Authors

  • Hikmat Ullah Jan Department of Botany, Government Superior Science College, Peshawar, Pakistan
  • Anis Saeed Department of Botany, Government Superior Science College, Peshawar, Pakistan
  • Gulnaz Parveen Department of Botany, Women University Swabi, Swabi, Pakistan
  • Naila Mukhtar Department of Botany, University of Okara, Okara, Pakistan
  • Muhammad Siraj Department of Botany, Islamia College University Peshawar, Pakistan
  • Zulqarnain Department of Botany, Government College Peshawar, Pakistan
  • Amtul Sami Department of Biotechnology, Women University Swabi, Pakistan
  • Muhammad Tayyab Gul Department of Botany, Qurtaba University, Hayatabad, Peshawar, Pakistan

DOI:

https://doi.org/10.53560/PPASB(60-2)743

Keywords:

Analgesic, Antispasmodic, Bark extracts, Boraginaceae, Ehretia acuminata, Pharmacological potential

Abstract

Ehretia acuminata, commonly known as “Puna” in Pakistan, is from the Boraginaceae family and is used in ecological, medicinal, and agricultural sectors. The current study was conducted to assess the pharmacognostic potency of bark extracts from E. acuminata. The crude distilled water, ethanol, and chloroform extracts signified a concentration-dependent increase in intestinal mobility of the experimented animal, and the plant delivered methodical proof for its pharmacological usage as an antispasmodic drug. The bark distilled water, bark ethanol, and bark chloroform extracts revealed antispasmodic potential (11±1, 9±1, and 11±1)  at 300 mg/kg. The distilled water, ethanol, and chloroform extracts also showed analgesic and muscle relaxant potential in the present study and the results were concentration dependent. The bark distilled water, bark ethanol, and bark chloroform extracts revealed the analgesic potential (10±1,16±1, and 11±1) at 300 mg/kg. The Bark distilled water, Bark ethanol, and Bark chloroform extracts revealed the muscle relaxant potential (6±1, 5±1, and 5±1) at 300 mg/kg. While the distilled water, ethanol and chloroform extracts did not show acute toxic effects against the tested animal mice. In this study, bark extracts of E. acuminata showed pharmacological potency in experimental animals. The plant delivered scientific proof for its pharmacological usage as an antispasmodic, acutely toxic, muscle relaxant, as well as an analgesic drug.

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Published

2023-06-24

How to Cite

Hikmat Ullah Jan, Anis Saeed, Gulnaz Parveen, Naila Mukhtar, Muhammad Siraj, Zulqarnain, Amtul Sami, & Muhammad Tayyab Gul. (2023). Pharmacognostic Study of Ehretia acuminata R.Br. Proceedings of the Pakistan Academy of Sciences: B. Life and Environmental Sciences, 60(2), 267–272. https://doi.org/10.53560/PPASB(60-2)743

Issue

Vol. 60 No. 2 (2023)

Section

Research Articles

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