Public Awareness and Bio-management of COVID-19 by Four Medicinal Herbs in District Bhimber, Azad Kashmir, Pakistan

Public Awareness and Bio-management of COVID-19 by Four Medicinal Herbs


  • Tanveer Hussain Department of Botany, Mirpur University of Science and Technology (MUST), Mirpur-10250 (Bhimber Campus, AJ&K), Pakistan
  • Muhammad Ishtiaq Department of Botany, Mirpur University of Science and Technology (MUST), Mirpur-10250 (Bhimber Campus, AJ&K), Pakistan


Medicinal herbs, Antiviral plants, Healing agents, Immunity enhancer, COVID-19


The current research work is focused on awareness and bio-management of COVID-19 through four selected natural medicinal herbs (MHs) in District Bhimber, Azad Jammu, and Kashmir (AJK), Pakistan. It was observed that the mortality rate is extremely high in people having weak immune systems, especially with pre-existing health problems. We have conducted questionnaire surveys protocol in different societies about COVID-19 assessment. After the field survey of the coronavirus, we used extracts of selected herbs against the patients of COVID-19 in a local hospital. In these preliminary experimental trials, we have tried to compile the effects of different MHs and their bioactive components that have the potential to combat the infection of COVID-19. The treatment of MHs can also be improved the immune system of the patients and future risk of viral attack can be minimized. The extracts of selected MHs (Allium sativum L, Zingiber officinale Roscoe, Piper nigrum L., and Vitex negundo L.) were given to
already symptomatic patients with COVID-19 in the District Headquarter (DHQ) hospital Bhimber, AJK. The crude extracts of MHs showed 90 % positive results against COVID-19 patients in the preliminary experimental trials. The ‘Allium sativum and Zingiber officinale’ were showed the best recovery rate with 95 % and 87 % respectively. Thus,  it was proved that MPHs can help in the reduction of the mortality rate. Therefore, it is concluded that the MHs have also been considered as the best healing agents against this epidemic virus as well as boost-up the immune system of human beings. This article will help research laboratories and industries in the identification and scrutinization of potential medicinal herbs against COVID-19 and other viruses as well in the future.


J.F.W. Chan., S. Yuan., K.H. Kok., K.K.W. To., H. Chu., J. Yang., F. Xing., J. Liu., C.C.Y. Yip., R.W.S. Poon, and H.W. Tsoi. A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster. The Lancet 395.10223: 514–523 (2020).

M.B. Mohamed., and M.A. Mahmoud. Effects of educational program on MERS Corona-Virus among nurses’ students at Jazan University. 1439-2017 (2018).

S.R. Weiss., and S. Navas-Martin. Coronavirus pathogenesis and the emerging pathogen severe acute respiratory syndrome coronavirus. Microbiology and molecular biology reviews 69.4: 635-664 (2005).

Y. Yang., F. Peng., R. Wang., K. Guan., T. Jiang., G. Xu., J. Sun., and C. Chang. The deadly coronaviruses: The 2003 SARS pandemic and the

novel coronavirus epidemic in China. Journal of autoimmunity 109: 102434 (2020).

S. Baharoon., and Z.A. Memish. “MERS-CoV as an emerging respiratory illness: a review of prevention methods.” Travel medicine and infectious disease 32: 101520 (2019).

D. Zhou., P. Zhang, C. Bao, Y. Zhang, and N. Zhu. Emerging understanding of etiology and epidemiology of the novel coronavirus (COVID-19) infection in Wuhan, China (2020).

M. Broberg. A critical appraisal of the world health organization’s international health regulations (2005) in times of pandemic: it is time for revision. European Journal of Risk Regulation 11.2: 202-209 (2020).

G. Capano., M. Howlett., D.S. Jarvis., M. Ramesh., and N. Goyal., Mobilizing policy (in) capacity to fight COVID-19: Understanding variations in state responses. Policy and Society 39.3: 285-308 (2020).

D. Hu., X. Lou., Z. Xu., N. Meng., Q. Xie., M. Zhang., Y. Zou., J. Liu., G. Sun., F. Wang. More effective strategies are required to strengthen public awareness of COVID-19: evidence from google trends. Journal of Global Health 10.1 (2020).

H.E. Randolph., and L.B. Barreiro. Herd immunity: understanding COVID-19 immunity. 52.5: 737-741 (2020).

S.A. Rabbani., F. Mustafa., and A. Mahtab. Middle East respiratory syndrome (MERS): awareness among future health care providers of United Arab Emirates. International Journal of Medicine and Public Health 10.1 (2020).

Y.H. Jin., L. Cai., Z.S. Cheng, H. Cheng, T. Deng, Y.P. Fan., C. Fang., D. Huang., L.Q. Huang., Q. Huang., and Y. Han. A rapid advice guideline for the diagnosis and treatment of 2019 novel coronavirus (2019-nCoV) infected pneumonia (standard

version). Military Medical Research 7.1:1-23 (2020).

M. Cherkaoui. The Shifting Geopolitics of Coronavirus and the Demise of Neoliberalism - (Part 2). Aljazeera Center for Studies, March, 19 (2020).

R. Schnall. National Institute of Health (NIH) funding patterns in Schools of Nursing: Who is funding nursing science research and who is conducting research at Schools of Nursing? Journal of Professional Nursing 36.1: 34-41 (2020).

F.S. Taccone., J. Gorham., and J.L. Vincent.Hydroxychloroquine in the management of critically ill patients with COVID-19: the need for

an evidence base. The Lancet Respiratory Medicine 8.6: 539-541 (2020).

S.A.A. Jassim., and M.A. Naji. Novel antiviral agents: a medicinal plant perspective. Journal of applied microbiology 95.3: 412-427 (2003).

W. Hussain., K.S. Haleem., I. Khan., I. Tauseef., S. Qayyum., B. Ahmed., and M.N. Riaz. Medicinal plants: a repository of antiviral metabolites. Future Virology 12.6: 299-308 (2017).

L.S. Alagu., R.M.B. Shafreen., A. Priya., and K.P. Shunmugiah. Ethnomedicines of Indian origin for combating COVID-19 infection by hampering the viral replication: Using structure-based drug discovery approach. Journal of Biomolecular Structure and Dynamics pp. 1–16 (2020).

M.N. Boukhatem., and W.N. Setzer. Aromatic herbs, medicinal plant-derived essential oils, and phytochemical extracts as potential therapies for coronaviruses: Future perspectives. Plants (Basel, Switzerland) 9.6: 800 (2020).

S. Li., C. Chen., H. Zhang., H. Guo., H. Wang., L. Wang., and P. Xiao. Identification of natural compounds with antiviral activities against SARSassociated coronavirus. Antiviral Research 67.1: 18–23 (2005).

C.W. Lin., F.J. Tsai., C.H. Tsai., C.C. Lai., L. Wan., T.Y. Ho., and P.D.L. Chao. Anti-SARS coronavirus 3C-like protease effects of Isatis indigotica root and plant-derived phenolic compounds. Antiviral Research 68.1: 36–42 (2005).

K.M. Lau, K.M. Lee., C.M. Koon., C.S.F. Cheung., C.P. Lau., H.M. Ho., and K.P. Fung. Immunomodulatory and anti-SARS activities of

Houttuynia cordata. Journal of Ethnopharmacology 118.1: 79–85 (2008).

I.G. Alghamdi., I.I. Hussain., S.S. Almalki., M.S. Alghamdi., M.M. Alghamdi., and M.A. El-Sheemy. The pattern of Middle East respiratory syndrome coronavirus in Saudi Arabia: a descriptive epidemiological analysis of data from the Saudi Ministry of Health. International journal of general medicine 7: 417 (2014).

T. Dudani., and A. Saraogi., Use of herbal medicines on coronavirus. Acta Scientific Pharmaceutical Sciences 4.2020: 61-63 (2020).

S. Shah., D. Chaple., S. Arora., S. Yende, K. Moharir, and G. Lohiya. Exploring the active constituents of Oroxylum indicum in intervention of novel coronavirus (COVID-19) based on molecular docking method. Network Modeling Analysis in Health Informatics and Bioinformatics 10.1: 1-12 (2021).

S. Bhakat., and M.E. Soliman. Chikungunya virus (CHIKV) inhibitors from natural sources: a medicinal chemistry perspective. Journal of natural medicines 69.4: 451-462 (2015).

Q.Q. Mao., X.Y. Xu., S.Y. Cao., R.Y. Gan., H. Corke., and H.B. Li. Bioactive compounds and bioactivities of ginger (Zingiber officinale Roscoe). Foods 8.6: 185 (2019).

M.O. Elgendy., A.O. El-Gendy., and M.E. Abdelrahim. Public awareness in Egypt about COVID-19 spread in the early phase of the

pandemic. Patient Education and Counseling 103.12: 2598-2601 (2020).

H. Alahdal., F. Basingab., and R. Alotaibi. An analytical study on the awareness, attitude and practice during the COVID-19 pandemic in Riyadh, Saudi Arabia. Journal of infection and public health 13.10: 1446-1452 (2020).

M. Sencanski., D. Radosevic., V. Perovic., B. Gemovic., M. Stanojevic., N. Veljkovic., and S. Glisic. Natural products as promising therapeutics for treatment of influenza disease. Current pharmaceutical design 21.38: 5573-5588 (2015).

L.C.P.V. Boas., M.L. Campos., R.L.A. Berlanda., N. de Carvalho Neves., and O.L. Franco. Antiviral peptides as promising therapeutic drugs. Cellular and Molecular Life Sciences 76.18: 3525-3542 (2019).

V. Balachandar., I. Mahalaxmi., J. Kaavya., G. Vivekanandhan., S. Ajithkumar., N. Arul., and S.M. Devi. COVID-19: emerging protective measures. European review for medical and pharmacological sciences 24.6: 3422-3425 (2020).

S. Kaushik., G. Jangra., V. Kundu., J.P. Yadav., and S. Kaushik. Anti-viral activity of Zingiber officinale (Ginger) ingredients against the Chikungunya virus. Virusdisease 31(3): 270-276 (2020).

R.R. Narkhede., A.V. Pise., R.S. Cheke., and S.D. Shinde. Recognition of natural products as potential inhibitors of COVID-19 main protease (Mpro): In-silico evidences. Natural products and Bioprospecting 10.5: 297-306 (2020).

H. Khanal., U. Khanal., and J. Koirala. Medicinal plant vasaka could be a therapeutic option for the management of COVID-19 symptoms. Journal of Medicinal Plants 8.5: 44-48 (2020).




How to Cite

Hussain, T. ., & Ishtiaq, . M. . (2021). Public Awareness and Bio-management of COVID-19 by Four Medicinal Herbs in District Bhimber, Azad Kashmir, Pakistan : Public Awareness and Bio-management of COVID-19 by Four Medicinal Herbs. Proceedings of the Pakistan Academy of Sciences: B. Life and Environmental Sciences, 58(S), 69–76. Retrieved from